What Lube Can You Use With Condoms? A Complete Guide Condoms National Here's your friendly reminder that pairing a quality condom with water based lube ensures a safer and better experience. IMPORTANT: Avoid using anything that contains oil such as lotion, Vaseline, or How to use condoms Protection works best when you use it right. Follow these simple #Condom do's and don'ts to take care of yourself and your partners.