Can You Donate Plasma if You Smoke Weed? What About Blood? Yes, you can donate blood if you smoke or consume cannabis. The recipient of the blood will not get high, another common MYTH. All donors go through the same health Driving After Taking Any Form of Marijuana Is Unsafe Smoking and vaping dont affect your eligibility to donate. Become a donor and give life today. Australian Red Cross Lifeblood Facebook FAQs Shepeard Blood